I like that Nature's Pearl has 650 mg of Muscadine Grape Seed and no fillers. Muscadine grapes are a great source of polyphenols. I am very pleased with this product and I use it in conjunction with my other health supplements.

The Nature Pearl product line is a good product. However, consumer alert here "¦ I was shipped three expired bottles that had to be returned.

I was diagnosed with a "connective tissue" problem two years ago by a Internist MD who is also a naturopath...very scientific guy who refuses to prescribe the usual AMA drug protocol. He prescribed this brand of Muscadine Grape Seed - which has been integral in healing this issue. This brand seems to work better than another brand I tried. I had a strain that healed in one day after dosing heavily with Nature's Pearl capsules . It was really like a miracle and I was in terrible pain. Here are some of the benefits of Musicadine Grape Seed extract from Dr. Mercola's web site - hope it helps:

Grape seeds are powerful antioxidants, and their extract is rich in proanthocyanidins. Scientific studies have shown the antioxidant power of proanthocyanidins is 20 times stronger than vitamin C and 50 times stronger than vitamin E.
Aside from helping to lower your blood pressure, grape seed extract may have a positive impact on a number of diseases including:
"¢ Leukemia
"¢ Skin cancer
"¢ Obesity
Grape seeds have also been shown to improve flexibility in joints, arteries and body tissues such as your heart, and research studies have shown grape seed helps improve blood circulation by strengthening capillaries, arteries and veins.

Resveratrol, meanwhile, is an antioxidant found in grape skins. It is making headlines because it appears to slow down aging and even increase the lifespan of human cells. It reduces oxidative stress damage to your cardiovascular system by neutralizing free radicals, and helps support your body's natural defenses.

Resveratrol is also unique among antioxidants because it can cross the blood-brain barrier to help protect your brain and nervous system, and studies show that its benefits are wide reaching, including:

"¢ Protecting your cells from free radical damage
"¢ Inhibiting the spread of cancer, especially prostate cancer
"¢ Lowering your blood pressure

"¢ Keeping your heart healthy and improving elasticity in your blood vessels
"¢ Normalizing your anti-inflammatory response
"¢ Helping to prevent Alzheimer's disease

I have tried others and they don't work as good.

My wife takes these religiously! A friend of hers raises the SPECIFIC strain of grapes use to make this product. Having ties with the grape producer who has ties with the developer /processor, we know that Big Pharma has tried to purchase the company who's studies have found a link between the body having more oxygen and less cancer (as cancer can't thrive in a high oxygen environment). Do you think Big Pharma wants to hush them up? Good product! Robert, RPh.