I was looking for yet anothe chondotin clucosmine supplement. I had been using puritan pride brand. The formulas on the label are nearly identical except for some of the propiety parts. I have waited to write a review until I have used a whole bottle, to eliminate any placebo effect. My knee feels much better hard to put into %, but the do all and end all is that I used to take lortab's to get thru the day. I haven't taken one in 2 weeks now! I take the 2 required pills at the same time in the am along with the rest of my meds, HBP, hi colesterol. When I had the synovisc injection about a yr ago the x rays of my knee showed not quite bone on bone but close. No I do use a couple of other products as needed. Pernatrex cream once maybe 2x a day or none at all. Pernatrex is not a "heat" cream. But befor I found the Bi flex I did feel the the Penetrex did help over time. I'm active so I can over extend myself chores, bycyceling etc. I favor time a a recumbant exercycle over walking so far. So in cases where I have done more and ger some breakthrough pain I use 2 different types of compression knee sleeves Copper fit (I don't care about the copper) $9.99 ea at bed bath and beyond 20% coupons are easily found so 7.99 since they look sort of like a nylon mostly worn with long pants (yea vanity) but for a higher ding I wear the sort of athletic ones the black ones elastic with 2 metal or fiber strips on each side. The I can tell prople yea football or sking accident when I was a kid.Again about $10 at CVS I think. All of this combination works for me, but the Bi-flex is the major player.

I suffer from chronic pain in all my joints - knee, wrist, fingers. This supplement does helps me to move around without too much pain. I do also take omega 3 and turmeric capsules (1000 mgs) to help reduce the swelling and pain. It helps me. This won't cure your pain but will make you feel better as long as you take it on a regular basis.

I take with hyaluronic acid capsules and in less than 3 weeks my knee pain has been greatly reduced. Because it was so successful for me I purchased the same mix in an equine product and in less than 3 weeks my horse (he has osteoarthritis in his knees) is no longer limping.

It is a very good product, but in July I found out I had a major problem swallowing these pills. I have to cut them into 8ths now to get them down my throat. Horrible thing to be gasping for air. I have since ordered what looks like smaller pills.

Amazing product, has helped me overcome major joint problems, broken bones, etc over the many years I've been using this. Only complaint with this formulation would be that it has too much manganese added, wish they would cut it down by at least half or more like 80% less would be ideal IMO.